Menopause is more than hot flushes. 

It is a whole-body transition that can affect bone strength, memory, cognitive clarity and overall wellbeing. 

From our mid 30s onwards, bone mineral density gradually begins to decline. During perimenopause and menopause, falling oestrogen levels can accelerate this process. At the same time, many women report experiencing forgetfulness, reduced concentration and brain fog. In fact, up to two thirds of women list memory changes as a menopause symptom. 

In a 12-month randomised, double blind, placebo-controlled study, 131 postmenopausal women received either specific collagen peptides or placebo daily. 

Bone mineral density was measured at the spine and femoral neck, alongside markers of bone turnover: 

• P1NP, a marker of bone formation 
• CTX 1, a marker of bone resorption 
• 102 participants completed the study. 

Results showed that women taking the specific collagen peptides experienced: 

• A significant increase in bone mineral density at the spine and femoral neck compared with placebo 
• Increased P1NP levels, indicating enhanced bone formation 
• Reduced CTX 1 levels compared to control, indicating reduced bone degradation 

These findings suggest that specific Bioactive Collagen Peptides® can positively influence bone formation and support bone mineral density in postmenopausal women. 

FORTIBONE® works by stimulating the body’s own collagen production within bone tissue, helping maintain the structural matrix that gives bone its strength and flexibility. 

12 Month Clinical Study in Postmenopausal Women (König et al., 2018) 

Bone is living tissue that is constantly being broken down and rebuilt. 

During menopause: 

• Oestrogen levels decline 
• Bone breakdown can outpace bone formation 
• Bone mineral density may reduce 

Over time, this can affect structural strength and long-term skeletal health. 

Supporting bone metabolism during midlife is essential for maintaining mobility and resilience later in life. 

Cognitive changes are commonly reported during menopause. Many women experience difficulty concentrating, forgetfulness and mental fatigue. 

Balance includes clinically studied KSM-66® Ashwagandha root extract, a botanical ingredient that has been studied for its effects on cognitive function and wellbeing. 

KSM-66® Ashwagandha root extract. and Memory: In a randomised, double blind study involving adults with mild cognitive impairment, participants received either KSM-66® Ashwagandha or placebo for 8 weeks. 

Cognitive performance was assessed using the Wechsler Memory Scale III. 

Participants taking Ashwagandha demonstrated: 

• Significant improvements in immediate and general memory compared with placebo 
• Improved attention 
• Improved executive function 

Ashwagandha and Climacteric Symptoms: In an 8-week double blind, randomised study involving 100 perimenopausal women with climacteric symptoms: 

• Participants receiving clinically studied KSM-66® Ashwagandha root extract reported significantly lower menopausal rating scale scores compared with placebo 
• Improvements were observed in menopause specific quality of life assessments 
• Hormonal parameters showed supportive changes, including increases in estradiol and reductions in luteinizing hormone 

These findings indicate that KSM-66® Ashwagandha root extract may support overall wellbeing during perimenopause.